{"product_id":"myths-and-verities-in-protein-folding-theories-hardcover","title":"Myths and Verities in Protein Folding Theories - Hardcover","description":"\u003cp\u003eby \u003cb\u003eArieh Ben-Naim\u003c\/b\u003e (Author)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eThis book tells the story of a whole field of research which went disastrously wrong in many different directions when the wrong tools were used and the wrong targets aimed at, to solve a problem.\u003c\/p\u003e\u003cp\u003eIt all started from the misinterpretation of Schellman's experiments which were carried out in the mid-1950s, and which were later encapsulated by the so-called \"Hydrogen-bond inventory argument.\" As a result, hydrogen bonding was ignored in protein folding; along with that a whole repertoire of other possible hydrophilic effects were not even considered. Against this background the hydrophobic effects, as suggested by Kauzmann, became the single most important effects in protein folding.\u003c\/p\u003e\u003cp\u003eIn addition, as a result of the misinterpretation of Anfinsen's hypothesis, as well as misunderstanding of the Second Law, people made futile attempts to search for the structure of proteins in the global minimum of either the Energy, or the Gibbs Energy Landscape.\u003c\/p\u003e\u003cdiv\u003e\n\u003cstrong\u003eNumber of Pages:\u003c\/strong\u003e 448\u003c\/div\u003e\u003cdiv\u003e\n\u003cstrong\u003eDimensions:\u003c\/strong\u003e 1.2 x 9.1 x 6.3 IN\u003c\/div\u003e\u003cdiv\u003e\n\u003cstrong\u003ePublication Date:\u003c\/strong\u003e February 24, 2016\u003c\/div\u003e","brand":"Books by splitShops","offers":[{"title":"Default Title","offer_id":42105228198023,"sku":"9789814725989","price":110.16,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/2623\/2711\/files\/bc479e8161abc560940b443249bcde28.webp?v=1732432302","url":"https:\/\/booksby.splitshops.com\/products\/myths-and-verities-in-protein-folding-theories-hardcover","provider":"Books by splitShops","version":"1.0","type":"link"}